Adelaide Proteomics Centre
The Adelaide Proteomics Centre is a joint venture of the Hanson Institute and University of Adelaide, established with support from the Australian Cancer Research Foundation. It offers researchers on campus and elsewhere in Adelaide, a state-of-the-art Proteomics facility. Proteomics describes the study of the entire protein complement present in a cell, organelle or tissue. Proteins provide the architecture of cells, effect metabolic processes and play a major role in transducing physiological or environmental regulatory signals. Within cells, the levels of individual proteins are dynamic and many proteins undergo modifications that affect their function and interaction with other proteins. These important processes underlie the ability of an organism to grow and maintain itself but may be altered in cases of disease such as cancer. Proteomics technology allows us to identify and characterize pathologically dysregulated proteins involved in disease processes. Many currently used drugs target protein molecules and understanding networks of protein interactions offers the prospect of development of new treatments for diseases.
The Proteomics centre has the latest mass spectrometry technology to identify proteins and characterize their post-translational modifications. The centre is equipped to quantify changes in protein expression levels using techniques such as 2-D Fluorescence Difference Gel Electrophoresis and isotopic labelling of complex protein mixtures. The proteomics facility is located in the Molecular Life Sciences Building (room 1.51) of the University of Adelaide. For further information on services, go to http://www.adelaide.edu.au/mbs/proteomics/
