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info iconRESEARCH MODULE
Group Leader - Principal Research Fellow, Head of Laboratory
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Ashley BLACKSHAW
Group Leader - Director of Nerve Gut Research
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John DENT
Group Leader - Director, Department of Gastroenterology, Hepatolo
Gerald HOLTMANN
Group
Stuart BRIERLEY , PhD
Amanda PAGE , PHd
Jenny PERSSON , PhD
Richard YOUNG , PhD
Marita BROBERG
Joel CASTRO , BSc (Hons)
Nicole COOPER , BSc (Hons)
Claudine FLACH , BSc
Montri GURURATSAKUL , MBBS
Andrea HARRINGTON , PhD
Patrick HUGHES , PhD
Christopher MARTIN , PhD
Melissa MORETTA , BSc (Hons)
Tracey ODONNELL , BSc
Nathan PROCTER , BSc (Hons)
Brigette CHIA
Stephen KENTISH
Nektaria PEZOS , BSc (Hons)
James SLATTERY , BSc (Hons)
Kate SUTHERLAND , BSc (Hons)
Jing YANG


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Nerve Gut Research Laboratory

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PROJECTS
How does inflammation of the gut change sensory nerves?

Mice develop similar microscopic changes in the colon after experimental inflammation to those seen in humans, so we can discover more from this model. We have

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Intestinal sensing mechanisms for glucose and their disruption in diabetes

In diabetic patients gastric emptying is often delayed following a meal, leading to nausea, impaired nutrition and delayed absorption of orally administered dru

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Mechanisms of mechanotransduction in primary visceral afferents

Mechanotransduction is responsible for the senses of touch and pain. In addition mechanosensory information reaches the brain from the viscera. This gives ris

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Novel treatments for Irritable Bowel Syndrome

Irritable bowel syndrome has a major impact on quality of life in up to 10% of the western population, through chronic pain and discomfort associated mainly wit

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Reflux inhibitor

Major, 12 yr old collaborative research program to find new treatments for gastro-oesophageal reflux disease. Reflux is caused by defective neural control of th

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Response of Peripheral Blood Mononuclear Cells to Substance P Stimulation in Patients with Irritable Bowel Syndrome and Functional Dyspepsia; Role of GNB3 Polymorphism

We aim to characterize potential functional and morphological alterations of immune-modulatory cells in patients with functional dyspepsia, irritable bowel synd

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The role of Proteinase activated- and Neurokinin receptors in the preventive and therapeutic effect of Escherichia coli Nissle 1917 on post-inflammatory visceral hyperalgesia in a rat model

Abdominal pain represents one of the most common reasons for primary care visits and consultation with a gastroenterologist. Acute gastrointestinal infections a

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