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Group Leader - Research Fellow, Molecular Ageing Laboratory
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Grant BUCHANAN , BSc (Hons), PhD
Group
Villis MARSHALL , MBBS, MD, FRACS
Eleanor NEED , BSc (Hons), PhD
Melissa O'LOUGHLIN
Andrew TROTTA , BSc (Hons)


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Publications from Molecular Ageing Laboratory

Sakko AJ, Ricciardelli C, Mayne K, Suwiwat S, Lebaron RG, Marshall VR, Tilley WD, Horsfall DJ, Modulation of prostate cancer cell attachment to matrix by versican., Cancer Research, 63:4786-4791, (2003)

James AJ, Agoulnik IU, Harris JM, Buchanan G, Tilley WD, Marcelli M, Lamb DJ, Weigel NL, A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity., Molecular Endocrinology, 16(12):2692-2705, (2002)

Buchanan G, Greenberg NM, Scher HI, Harris JM, Marshall VR, Tilley WD, Collocation of androgen receptor gene mutations in prostate cancer., Clinical Cancer Research, 7(5):1273-1281, (2001)

Buchanan G, Irvine RA, Coetzee GA, Tilley WD, Contribution of the androgen receptor to prostate cancer predisposition and progression., 20(38810):207-223, (2001)

Han GZ, Foster BA, Mistry S, Buchanan G, Harris JM, Tilley WD, Greenberg NM, Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer., Journal of Biological Chemistry, 276(14):11204-11213, (2001)

Buchanan G, Yang MO, Harris JM, Nahm HS, Han GZ, Moore N, Bentel JM, Matusik RJ, Horsfall DJ, Marshall VR, Greenberg NM, Tilley WD, Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function., Molecular Endocrinology, 15(1):46-56, (2001)

Park JJ, Irvine RA, Buchanan G, Koh SS, Park JM, Tilley WD, Stallcup MR, Press MF, Coetzee GA, Breast cancer susceptibility gene 1 (BRCA1) is a coactivator of the androgen receptor., Cancer Research, 60(21):5946-5949, (2000)

Ricciardelli C, Mayne K, Sykes PJ, Raymond WA, McCaul K, Marshall VR, Horsfall DJ, Elevated levels of versican but not decorin predict disease progression in early-stage prostate cancer., Clinical Cancer Research, 4(4):963-971, (1998)

Zhang SXD, Bentel JM, Ricciardelli C, Horsfall DJ, Haagensen DE, Marshall VR, Tilley WD, Immunolocalization of apolipoprotein D, androgen receptor and prostate specific antigen in early stage prostate cancers., Journal of Urology, 159(2):548-554, (1998)

Bentel JM, Buchanan G, Tilley WD, Androgen receptor gene mutations in prostate cancer., rostate:219-244, (1997)

Ricciardelli C, Mayne K, Sykes PJ, Raymond WA, McCaul K, Marshall VR, Tilley WD, Skinner JM, Horsfall DJ, Elevated stromal chondroitin sulfate glycosaminoglycan predicts progression in early-stage prostate cancer., Clinical Cancer Research, 3(6):983-992, (1997)

Tilley WD, Buchanan G, Hickey TE, Bentel JM, Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence., Clinical Cancer Research, 2(2):277-285, (1996)

Aspinall JO, Bentel JM, Horsfall DJ, Haagensen DE, Marshall VR, Tilley WD, Differential expression of apolipoprotein-d and prostate-specific antigen in benign and malignant prostate tissues., Journal of Urology, 154(2):622-628, (1995)

Horsfall DJ, Mayne K, Ricciardelli C, Rao M, Skinner JM, Henderson DW, Marshall VR, Tilley WD, Age-related-changes in guinea-pig prostatic stroma., Laboratory Investigation, 70(5):753-763, (1994)

Tilley WD, Limtio SS, Horsfall DJ, Aspinall JO, Marshall VR, Skinner JM, Detection of discrete androgen receptor epitopes in prostate-cancer by immunostaining - measurement by color video image-analysis., Cancer Research, 54(15):4096-4102, (1994)

Ricciardelli C, Horsfall DJ, Sykes PJ, Marshall VR, Tilley WD, Effects of estradiol-17-beta and 5-alpha-dihydrotestosterone on guinea-pig prostate smooth-muscle cell-proliferation and steroid-receptor expression in-vitro., 140(3):373-383, (1994)

Horsfall DJ, Mayne K, Skinner JM, Saccone GTP, Marshall VR, Tilley WD, Glycosaminoglycans of guinea-pig prostate fibromuscular stroma - influence of estrogen and androgen on levels and location of chondroitin sulfate., 25(6):320-332, (1994)

Miller J, Horsfall DJ, Skinner JM, Rao DM, Leong ASY, Marshall VR, Nuclear shape and prognosis following orchiectomy in stage D-2 prostate-cancer., Prostate, 24(6):306-312, (1994)

Miller J, Horsfall DJ, Marshall VR, Rao DM, Leong ASY, The prognostic value of deoxyribonucleic-acid flow cytometric analysis in stage-D2 prostatic-carcinoma., Journal of Urology, 145(6):1192-1196, (1991)

Ricciardelli C, Horsfall DJ, Skinner JM, Henderson DW, Marshall VR, Tilley WD, Development and characterization of primary cultures of smooth-muscle cells from the fibromuscular stroma of the guinea-pig prostate., Journal of Steroid Biochemistry, 25(11):1016-1024, (1989)

Tilley WD, Horsfall DJ, Skinner JM, Henderson DW, Marshall VR, Effect of pubertal development on estrogen-receptor levels and stromal morphology in the guinea-pig prostate., 15(2):195-210, (1989)

Horsfall DJ, Goldsmith KG, Ricciardelli C, Skinner JM, Tilley WD, Marshall VR, Steroid-hormone and epidermal growth-factor receptors in meningiomas., Australian and New Zealand Journal of Surgery, 59(11):881-888, (1989)

Tilley WD, Horsfall DJ, McGee MA, Alderman JE, Marshall VR, Effects of aging and hormonal manipulations on the level of estrogen-receptors in the guinea-pig prostate., 112(1):139-144, (1987)

Marshall VR, Tilley WD, Horsfall DJ, Localization and regulation of the prostatic estrogen-receptor., British Journal of Urology, 59(2):182-182, (1987)

James MJ, Nacey JN, Brennan JS, Marshall VR, An improved method for the preparation and culture of urothelial cells., Journal of Urology, 136(5):1141-1142, (1986)

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